IUD Treatment Could Prove Boon for Uterine Cancer Patients

The Italian researchers have revealed that the younger women affected with early-stage uterine cancer can be given treatment by using an intrauterine device that discharges a progestin hormone, which could prove effective.

The study was published online in Annals of Oncology. It concluded that the IUD women could enjoy the fertility and have families even if they defer their treatment of a total hysterectomy.

Hysterectomy affects fertility of women affected with endometrial cancer, so researches wanted to explore another option that along with preserving the fertility also treats uterine cancer.

Dr. Angeles Alvarez Secord, Associate Professor of gynecologic oncology at Duke Comprehensive Cancer Center in Durham, N. C. expressed that he had been employing IUD on patients who didn't want to affect their fertility or who didn't want to undergo surgery. He applauded the treatment and the study which will assist doctor to carry out better treatment.

IUD method is not approved for endometrial cancer yet, but is used for treating endometriosis and abnormal uterine bleeding.

The trials were carried out on 20 Italian patients from January 1996 to June 2009 suffering with atypical endometrial hyperplasia (AEH) and 14 women with early-stage endometrial cancer aged 20-40. The participants were given the treatment by inserting IUD called as Mirena for a year, along with the monthly injections of gonadotropin-releasing hormone (GnRH).

It was discovered that initially in 95% of women with AEH, lesions vanished completely and the treatment proved boon for 57.1% of women with early-stage cancer. Though, one of the women with AEH and four of the women with early-stage cancer witnessed advancement of disease, but all were alive by the end of the study.